Job Information

Bristol Myers Squibb Principal Scientist - Electron Microscopy in Princeton, New Jersey

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: .

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

BMS encompasses a broad range of disciplines to enable a robust pipeline of drug candidates aimed at serious diseases. Chemistry is a core capability in Small Molecule & Drug Discovery with innovative scientists working in medicinal chemistry, radiochemistry, analytical chemistry, and large-scale synthesis. Within SMDD our Lead Discovery and Optimization (LDO) team is responsible for high throughput screening, compound storage and distribution, primary assays to support discovery programs, and compound profiling to explore drug liabilities in vitro. LDO scientists discover and adopt cutting edge assay technologies that utilize state-of-the-art automation to drive speed and efficiency. Our Molecular Structure and Design team embraces novel approaches to computer-aided drug design, machine learning, and structural biology. The integration of these disciplines provides a seamless and highly interactive environment for discovery scientists to learn, develop, and innovate. Working in partnership with our disease area experts in the Thematic Research Centers provides an exciting pathway to discover and deliver medicines to patients in need.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

In the role as a Principal scientist within Molecular Structure and Design, the ideal candidate’s responsibilities will be to:

  • Maintain and supervise the day-to-day operations of a cryoEM facility including a Titan Krios microscope and IT data management to ensure smooth operation and best quality data acquisition.

  • Train and mentor scientists in sample preparation and EM data collection.

  • Support cryo-EM data collection needs for Molecular Structure & Design Structural Biology group and may aid cryo-EM data collection needs for other functional groups.

  • Support and interact with research program leaders and scientists to enable protein structure determination by cryoEM in support of drug discovery projects.

  • Develop and implement proactive approaches to new technology and processes including micro-ED and cryo-ET platforms

  • May lead initiatives related to continuous improvement or development of new approaches / technologies within a department / function

Present supportive arguments for complex ideas and projects to multidisciplinary, cross-departmental meetings in a way that persuades them to adopt a different point of view, when appropriate.

Basic Qualifications:

Bachelor’s Degree with 8+ years of academic and / or industry experience


Master’s Degree with 6+ years of academic and / or industry experience


Ph.D. or equivalent advanced degree in the Life Sciences, Chemistry, Physics or related stream with 4+ years of academic and / or industry experience

Preferred Qualifications:

  • Ph.D. in Biochemistry, Structural Biology, Molecular Biology, or related field with 4+ years of academic and / or industry experience working in a laboratory-based research setting.

  • Experience in operation and maintenance of an EM facility.

  • Requires advanced knowledge of principles, concepts and / or methodologies applicable to a wide range of work in the field of electron microscopy.

  • A record of scientific publication employing the skills listed above.

  • Familiarity with experiment documentation using electronic lab notebook and laboratory information management system (LIMS) systems.

  • Strong written and oral communication skills are required.

  • Applicants should be detail-oriented, highly organized, and able to multi-task with multiple projects.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to . Visit ( eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Company: Bristol Myers Squibb

Req Number: R1569813

Updated: 2023-05-30 01:04:26.863 UTC

Location: Princeton,New Jersey

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.