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UPMC Research Technician, Novasenta in Pittsburgh, Pennsylvania

Description

Purpose:

Performs laboratory activities to support therapy development efforts of Novasenta Inc., a UPMC Enterprises funded biotech startup focused on developing new cancer therapies targeting immunoregulatory mechanisms in the tumor microenvironment, reporting to Principal Scientist.

Responsibilities:

• Reports to Principal Scientist to ensure meeting the goals of Novasenta and pursuing the most promising targets within the tumor microenvironment for the development of therapeutics

• Conducts routine and non-routine lab procedures and assays for molecular, cellular and metabolic characterization of relevant samples from mouse models of cancer and human clinical cancer tissue under the supervision of Principal Scientist

• Assists experimental team members in biological, immunological assay development to investigate mechanisms of immune-mediated effects of novel identified targets

• As needed, supports the development and validation of new technologies for molecular, cellular and metabolic characterization of samples

• Documents and maintains a detailed and precise record of work performed

• Performs lab managerial, which includes ordering supplies and maintaining inventory, ensuring safety, service and maintain laboratory instruments of the lab, etc.

• Other job duties as assigned

What we offer you:

• Impact opportunity to drive inventions that can change the trajectory of cancer care for patients

• Competitive pay and benefits package.

• A dynamic, fast-paced startup culture combined with the stability of a well-established entity (UPMC).

• Work with some of the leaders in the immunotherapy and cancer field.

Qualifications

• Bachelor’s degree in biology, biochemistry, or closed related field with 1-2 years of experience in industry or academic research lab setting

• Basic skills in laboratory techniques

• Prior research experience desired experience with several of the following relevant techniques:

o Mammalian cell culture

o Flow cytometry and cell sorting

o Molecular biology techniques (e.g., PCR, development of genetic constructs, cloning, primer design, etc.)

o NGS (WGS, WES or RNAseq, including preparation of genomic libraries)

o Processing and characterization of fresh human tumor samples

• Experience with Prism, Flowjo, MS office is desired

• Experience in working under GLP standards and ensuring safety compliance under BSL-2

• Experience with laboratory information system (LIMS) is a plus

• Good verbal and written communication skills and the ability to interpret, summarize, and present results in a clear, concise, accurate manner

• Must be team oriented and able to work in a highly collaborative and interactive work environment to complete complex tasks

• Must be able to manage multiple and rapidly changing priorities and have ability to quickly learn new skills

• Must be detail-oriented and well organized

Licensure, Certifications, and Clearances:

UPMC is an Equal Opportunity Employer/Disability/Veteran

REQNUMBER: 309285548

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