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At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

We are seeking an exceptionally qualified experimental genome scientist to join the emerging Lilly Genomic Sciences team at Eli Lilly. The successful candidate will have the opportunity to help shape the vision of the Lilly Genomic Sciences team from the ground up, and to contribute to a diverse array of research projects spanning multiple therapeutic areas and data types. In this role, the selected candidate will lead experimental research initiatives using state-of-the-art functional genomics approaches and platforms while leveraging other advanced data generation modalities.

The ideal candidate will be a thought leader with excellent scientific communication skills, who has a deep knowledge of molecular biology, gene regulation, and human genetics; and who has a substantial track record of generating and leading the generation of high-quality data. They will spearhead close collaborations with computational counterparts who are using state of the art analysis approaches to interpret functional genomics data and leverage its use for ongoing drug development efforts at Lilly. A strong background in performing NGS–based screens (e.g. MPRA, STARR-seq, CRISPR regulatory element screening, deep mutational scanning, etc.) and genomics assays (e.g. ChIP-seq, ATAC-seq, Hi-C, etc.) is essential.

Key Responsibilities:

• Intellectually contribute to the development of a vibrant team of genome scientists who are fiercely dedicated to the application of state-of-the-art genomics approaches to pharmaceutical innovation

• Establish, implement, and execute highly robust and reproducible experimental strategies related to high-throughput quantitative biology

• Continue to develop, implement, and execute advanced genomics technologies, such as MPRA/STARR-seq, CRISPRi/a, and single-cell omics to drive functional genomics insights for drug discovery, target validation, and AI/ML modeling initiatives

• Design, optimize, and implement experiments using complex screening models, including cell lines, primary cells, differentiated cell types and in vivo systems.

• Drive technology innovation to streamline workflows, increase throughput, and enhance data quality in high-throughput assays

• Present scientific findings and progress to internal and external stakeholders, contributing to publications, patents, and conference presentations

• Mentor, train, and professionally develop research scientists and staff within the team

• While not the primary focus, this role may involve some genomics data analysis.

Basic Qualifications:

• A Ph.D. in genomics, genetics, molecular biology, or a related scientific field with 3+ years relevant industry or academic research experience (can include post doctoral experience).

Additional Skills/Preferences:

• A deep knowledge of genomics, and hands on experience implementing, troubleshooting, and developing genomics assays

• A proven track record of high performance on highly collaborative interdisciplinary functional genomics teams

• Cross-training in computational biology strongly preferred

• Ability to clearly communicate scientific material, efficiently manage time, and work collaboratively

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$133,500 - $217,800

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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